Melatonin (Mel) – DM6 Health

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Melatonin (Mel)

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What is melatonin and what is it used for in the body?

Melatonin is a hormone that is produced by the pineal gland in the brain. It is involved in the regulation of sleep-wake cycles and has been shown to have antioxidant and anti-inflammatory effects in the body. Melatonin is also involved in the regulation of the immune system and may have potential therapeutic uses in a variety of medical conditions.

How is melatonin measured in the body?

Melatonin can be measured in the body through various laboratory tests, including blood tests, urine tests, and saliva tests. In these tests, melatonin levels are typically measured in nanograms per milliliter (ng/mL).

What is the normal range for melatonin levels in the body?

The normal range for melatonin levels in the body varies depending on the method used to measure it and the specific laboratory that performs the test. In general, normal melatonin levels in the blood are typically between 1 and 20 ng/mL. In urine, normal melatonin levels are typically between 20 and 100 ng/mL. In saliva, normal melatonin levels are typically between 0.5 and 5 ng/mL.

What can cause abnormal melatonin levels in the body?

Abnormal melatonin levels in the body can be caused by a variety of factors, including medical conditions such as insomnia and jet lag, as well as certain medications and lifestyle factors (e.g. exposure to bright light at night).

How is melatonin related to the treatment of insomnia?

Melatonin has been shown to be effective in the treatment of insomnia, particularly in individuals with disrupted sleep-wake cycles (e.g. shift workers, travelers with jet lag). It is thought to work by regulating the body's internal clock and helping to promote sleep. Melatonin levels may be measured as part of the diagnostic process for insomnia, and melatonin supplements may be used as a treatment option in some cases.

How is melatonin related to the treatment of other medical conditions?

Melatonin has been shown to have potential therapeutic uses in a variety of medical conditions, including anxiety, depression, migraines, and tinnitus. However, more research is needed to fully understand the role of melatonin in the treatment of these conditions.

Are there any potential side effects associated with melatonin supplements?

Melatonin supplements are generally considered safe, with few reported side effects. However, some people may experience side effects such as headache, dizziness, or drowsiness when taking melatonin. It is important to consult a healthcare provider before starting any supplement regimen.

REFERENCES:

"Melatonin." MedlinePlus, U.S. National Library of Medicine, medlineplus.gov/druginfo/natural/940.html.

"Melatonin Test." Mayo Clinic, Mayo Foundation for Medical Education and Research, 26 Mar. 2020, mayoclinic.org/tests-procedures/melatonin-test/about/pac-20385240.

"Melatonin." Lab Tests Online, American Association for Clinical Chemistry, labtestsonline.org/tests/melatonin.

"The Role of Melatonin in the Management of Insomnia." Sleep Medicine Reviews, vol. 35, 2018, pp. 28-38., doi:10.1016/j.smrv.2017.06.002.